From Brussels E40 towards Oostende. N44 towards Aalter. N49 towards Knokke. Turn Sluis. At St. Anna ter Muiden. Left: Sluis / St. Annastraat. From Antwerp N49 towards Brugge/Knooke. Turn Sluis. At St. Anna ter Muiden. Left: Sluis / St. Annastraat. From Breda A1 towards Antwerp N49 towards Knokke/Brugge. Turn: Sluis. At St. Anna ter Muiden. Left: Sluis/St. Annastraat. From Rotterdam A16 towards Breda A17 towards Roosendaal A58. Towards Goes via Westerscheldetunnel. Towards Terneuzen N61. Towards Schoondijke N58 till Sluis. Follow the sign ‘centre’ from the round point at Sluis. Before the St Annastreet: Follow the signs towards Knokke, while you are driving through the city Sluis.